"Mifepristone": reviews about the drug
"Mifepristone" is a synthetic drug,directed or to prevent pregnancy, or to interrupt it. Getting into the blood of a woman, it blocks the action of hormones responsible for the onset of pregnancy and its further development. Under its action, the uterus is shortened and its inner layer - the endometrium - is rejected.
To this layer is attached a fertilized egg - this is the so-called beginning of pregnancy. If the pregnancy has already occurred, then the egg is rejected from the woman's body along with the endometrium.
Indications for use
The drug "Mifepristone", reviews of womentestify, is used only for the forced interruption of pregnancy on a short term (up to 6 weeks). After this period, this medicine should not be used. The effectiveness of the drug is 98%.
With normal, full-term pregnancy, the drug "Mifepristone" can be used to stimulate delivery.
It is prescribed for the treatment of uterine fibroids.
Used for emergency contraception. The efficiency is 99%.
Dosing and Administration
During pregnancy, taking this medicationleads to the opening of the uterus and the rejection of the endometrium usually in 46-48 hours. Two days later, the patient is prescribed prostaglandin, which, together with the drug "Mifepristone", helps reduce the uterus and leads to an artificial abortion.
The drug "Mifepristone", reviews of patients talk about this, once applied in the presence of a doctor. The dose is 600 mg.
After that, the woman is obligatoryis observed by the medical staff for at least 2 hours. After two days, ultrasound is mandatory, after half a month - a repeated ultrasound of the uterus and a clinical examination to ensure complete removal of the fetus.
Several years ago, 12 deaths occurred in the United States,associated with the use of the drug "Mifepristone" during childbirth. In all cases death from toxic shock was recorded. This was due to a decrease in women's local immunity due to the fact that they made the analogue of prostaglandins vaginally.
Contraindications for use
The drug can be prescribed if a woman has a number of contraindications to its use.
Therefore, its use is prohibited if:
- individual intolerance to the drug has been determined;
- pregnancy is not confirmed or exceedsfor a period of 6 weeks (after the termination of menstruation), or occurred during the use of intrauterine contraceptives, or after the abolition of hormonal contraceptives;
- there is a suspicion of ectopic pregnancy;
- a woman has a uterine myoma;
- the patient suffers from renal, adrenal or hepatic insufficiency;
- a woman has inflammatory diseases of the vagina;
- the patient has anemia.
With bronchial asthma, chronic diseaselungs, high blood pressure, heart failure drug "Mifepristone" (reviews of patients and recommendations of doctors say this) should be used cautiously. When taking Mifepristone, there may be various side effects in the form of aching pain in the lower abdomen, weakness, dizziness and severe headache. In 5% of women, there is abundant uterine bleeding, infection or inflammation of the uterus and appendages. The chair may be disturbed, nausea and vomiting, increased fever and even allergic reactions of the body in the form of rashes and urticaria.
Mifepristone: reviews and recommendations
After applying the drug, you must stop breastfeeding for three days.
After the termination of pregnancy, a new one may immediately come, which is highly undesirable. Therefore, the use of contraceptives is necessary.
In pharmacies, you can find drugs "Mifepristone" and "Mifegin", acting on the basis of the substance mifepristone.